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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SCNN1B
All Species:
24.15
Human Site:
S635
Identified Species:
53.13
UniProt:
P51168
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51168
NP_000327.2
640
72659
S635
L
D
V
I
E
S
D
S
E
G
D
A
I
_
_
Chimpanzee
Pan troglodytes
O46547
638
70169
Rhesus Macaque
Macaca mulatta
XP_001093815
640
72468
S635
L
D
V
I
E
S
D
S
E
G
D
A
I
_
_
Dog
Lupus familis
XP_547092
641
72636
S636
L
D
V
I
E
S
D
S
E
G
D
A
I
_
_
Cat
Felis silvestris
Mouse
Mus musculus
Q9WU38
638
72178
S633
L
D
T
M
E
S
D
S
E
V
E
A
I
_
_
Rat
Rattus norvegicus
P37090
638
71976
S633
L
D
T
M
E
S
D
S
E
V
E
A
I
_
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510121
645
72890
S640
L
D
V
I
E
S
D
S
E
A
E
N
A
_
_
Chicken
Gallus gallus
Q92075
637
73218
G632
P
C
G
P
S
K
D
G
E
T
G
L
E
_
_
Frog
Xenopus laevis
P51169
647
73958
S642
V
N
T
A
E
P
V
S
S
D
E
E
N
_
_
Zebra Danio
Brachydanio rerio
Q708S6
529
60016
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q21974
777
89110
S770
D
E
V
S
T
N
E
S
T
K
E
L
M
S
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
24
97.3
87.5
N.A.
83.9
83.4
N.A.
75.6
35.6
60.4
24.2
N.A.
N.A.
N.A.
25.7
N.A.
Protein Similarity:
100
41.5
98.7
94
N.A.
90.9
90.4
N.A.
87.5
54.5
76.6
41.8
N.A.
N.A.
N.A.
43.3
N.A.
P-Site Identity:
100
0
100
100
N.A.
69.2
69.2
N.A.
69.2
15.3
15.3
0
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
100
0
100
100
N.A.
84.6
84.6
N.A.
76.9
15.3
38.4
0
N.A.
N.A.
N.A.
46.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
0
0
0
10
0
46
10
0
0
% A
% Cys:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
55
0
0
0
0
64
0
0
10
28
0
0
0
0
% D
% Glu:
0
10
0
0
64
0
10
0
64
0
46
10
10
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
10
0
0
0
0
10
0
28
10
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
37
0
0
0
0
0
0
0
0
46
0
0
% I
% Lys:
0
0
0
0
0
10
0
0
0
10
0
0
0
0
10
% K
% Leu:
55
0
0
0
0
0
0
0
0
0
0
19
0
0
0
% L
% Met:
0
0
0
19
0
0
0
0
0
0
0
0
10
0
0
% M
% Asn:
0
10
0
0
0
10
0
0
0
0
0
10
10
0
0
% N
% Pro:
10
0
0
10
0
10
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
10
10
55
0
73
10
0
0
0
0
10
0
% S
% Thr:
0
0
28
0
10
0
0
0
10
10
0
0
0
0
0
% T
% Val:
10
0
46
0
0
0
10
0
0
19
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
73
73
% _